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Liz Greenfield, MS, APRN, IFMCP
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Elizabeth Greenfield — a San Francisco Bay Area clinician specializing in personalized, lab-driven hormone and gut health care for midlife women, differentiated by use of functional testing and DNA me
Your biological age and your hormonal health are not separate issues.
They are connected at the most fundamental level of your biology.
When we measure biological age using DNA methylation testing, we are looking at how your cells are actually aging compared to your chronological years. And one of the most powerful drivers of accelerated biological aging in women over 40 is dysregulated hormones.
Estrogen is not just about your menstrual cycle or hot flashes. It is neuroprotective. It supports mitochondrial function. It influences how your DNA is methylated and repaired.
Progesterone is not just a reproductive hormone. It calms the nervous system. It affects sleep architecture. It modulates inflammation.
When these hormones decline or become imbalanced during perimenopause, the downstream effects show up everywhere. Brain fog. Poor sleep. Fatigue that doesn't resolve with rest. Weight that shifts despite doing everything right. Mood changes that feel disproportionate to your stress level.
And if we measure biological age during this window, we often see acceleration.
This is not inevitable. It is reversible.
But it requires more than symptom management. It requires understanding what is actually driving the hormonal dysregulation in the first place. Cortisol patterns. Nutrient deficiencies. Gut dysfunction. Sleep disruption. Toxin exposure. All of these influence how your hormones function and how your cells age.
The women I work with are not just optimizing hormones. They are reversing biological age. Because when we address the root causes and restore hormonal balance within the context of the whole system, the epigenetic markers change.
We can measure that change. We can track it over time. And it changes the trajectory of the second half of life.
If you are in your 40s or 50s and feel like something is off despite doing everything right, this is the work that matters.
Your chronological age is fixed. Your biological age is not.
Book a discovery call to learn your biological age and what it means for your health trajectory.
https://lizgreenfield.kartra.com/calendar/book-with-liz
#longevityscience #biologicalage